A New Noroleanane from the Seeds of Trichosanthes kirilowii

Authors：Xu, Liang; Tang, Chun Feng; Wu, Cui; Ma, Yu Cui; Chao, Zhi Mao^*

Source：Natural Product Communications, 2018, 13(7): 813-815.

• Trichosanthes kirilowii
• Cucurbitaceae
• Karounitriol
• Noroleanane
• Pentacyclic triterpene

A new noroleanane named as karounitriol (1), together with four known compounds, 7-oxodihydrokarounidiol (2), isokarounidiol (3), karounidiol (4), and stigmasta-7,22-dien-3 beta-ol were isolated from the seeds of Trichosanthes kirilowii Maxim. Structure of the new compound was elucidated as 3 alpha,7 beta,29-trihydroxy-D:C-friedo-olean-8-ene on the basis of spectroscopic methods including extensive ID NMR (H-1, C-13), 2D NMR (H-1-H-1 COSY, DEPT, HMQC, HMBC, and NOESY), IR, and MS studies.

• Institution
  广西壮族自治区药用植物园