Motif orientation matters: structural characterization of TEAD1 recognition of genomic DNA

作者：Růžena Filandrová; Karel Vališ; Jiří Černý; Josef Chmelík; Lukáš Slavata; Jan Fiala; Michal Rosůlek; Daniel Kavan; Petr Man; Tomáš Chum; Marek Cebecauer; Daniele Fabris; Petr Novák

来源：Structure with Folding & design, 2020.

DOI：10.1016/j.str.2020.11.018

• TEAD1
• DNA binding
• M-CAT
• transcription factor
• structural mass spectrometry
• high- and low-affinity binding sites
• native electrospray
• hydrogen-deuterium exchange
• chemical cross-linking and single molecule FRET

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• 单位
  Charles University