A simple iodine-DMSO-promoted multicomponent reaction for the synthesis of 2,4-disubstituted dihydrotriazole-3-ones

作者：Liao, Hui; Huang, Zesheng; Zhu, Qiuhua^*

来源：Organic and Biomolecular Chemistry, 2022, 20(18): 3721-3725.

DOI：10.1039/d2ob00352j

• AGGREGATION-INDUCED EMISSION
• RACEMIC C6-UNSUBSTITUTED TETRAHYDROPYRIMIDINES
• STRUCTURE-PROPERTY RELATIONSHIP
• ONE-POT SYNTHESIS
• SP(2) C-H
• DERIVATIVES
• DESIGN
• SERIES
• PHARMACOLOGY
• 2-OXINDOLES

A series of 2,4-disubstituted 1,2,4-triazole-3-ones 4 were prepared via an iodine-DMSO-promoted three-component reaction of formaldehyde, amines and hydrazines in moderate yields.

• 单位
  南方医科大学