Transposon-Associated CRISPR-Cas System: A Powerful DNA Insertion Tool

作者:Ma, Wang; Xu, Ying-Shuang; Sun, Xiao-Man*; Huang, He*
来源:Trends in Microbiology, 2021, 29(7): 565-568.
DOI:10.1016/j.tim.2021.01.017

摘要

The transposon-associated CRISPR-Cas systemis emerging as a powerful tool for targeted genetic manipulation. Using this system, targeted genomic knockins and knockouts can be achieved, independently of the host-cell repair machinery, thereby significantly improving our ability to perform genome editing in a wider variety of cell types.

  • 单位
    南京师范大学

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