Dba-free palladium intermediates of the Heck-Matsuda reaction

Authors：MacHado Angelo H L; Milagre Humberto M S; Eberlin Livia S; Sabino Adão A; Correia Carlos Roque D^*; Eberlin Marcos N

Source：Organic and Biomolecular Chemistry, 2013, 11(20).

DOI：10.1039/c3ob40142a

• Catalytic cycles
• Heck-matsuda reactions
• Palladium intermediates
• Palladium species
• Transient complexes
• Wacker-type reactions

The "dba-free" Heck-Matsuda reaction was investigated via direct ESI-MS(/MS) monitoring. Palladium species involved in the reduction of Pd(ii) during a Wacker type reaction and several "dba-free" arylpalladium transient complexes were detected and characterized. Based on these findings, a more comprehensible catalytic cycle for this pivotal reaction is suggested.