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Genome-wide Profiling Identifies DNA Methylation Signatures of Aging in Rod Photoreceptors Associated with Alterations in Energy Metabolism
作者:Ximena Corso-Díaz; James Gentry; Ryan Rebernick; Catherine Jaeger; Matthew J. Brooks; Freekje van Asten; Keshav Kooragayala; Linn Gieser; Jacob Nellissery; Raul Covian; Tiziana Cogliati; Anupam K. Mondal; Ke Jiang; Anand Swaroop
来源:
Cell Reports
, 2020, 31(3): 107525.
DOI:10.1016/j.celrep.2020.107525
retinal aging
epigenome
DNA methylome
gene regulation
rod photoreceptor
mitochondria
differential methylation clusters
beta oxidation
摘要
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单位
National Institutes of Health
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