Facile synthesis of N2-substituted-1,2,3-triazole from aryl ethynylene and azide via a one-pot two-step strategy

作者：Guan, Cong; Ji, Jian; Li, Zi; Wei, Qinghua; Wu, Xiang; Liu, Shunying^*

来源：Tetrahedron, 2022, 108: 132670.

DOI：10.1016/j.tet.2022.132670

• 1,2,3-Triazole
• One-pot two-step strategy
• Radical transformation
• Facile synthesis

An efficient one-pot two-step synthetic strategy to access highly selective N-2-substituted-1,2,3-triazole from aryl ethynylenes, azides and furan has been developed via a radical transformation. 17 examples of aryl ethynylene with various substituents were converted into their corresponding functionalized N-2-substituted-1,2,3-triazole derivatives in good yields.