An efficient transition metal-free difunctionalization of alkenes in water for the green preparation of sulfone compounds

作者：Yang, Guang; Wang, Shoucai; Nie, Hongsheng; Xiong, Zhicheng; Li, Xuan; Ji, Fanghua^*; Jiang, Guangbin^*

来源：Applied Organometallic Chemistry, 2022, 36(1): e6470.

DOI：10.1002/aoc.6470

• alkenes
• difunctionalization
• quinoxalin-2(1H)-ones
• sulfones
• transition metal free

A direct difunctionalization method of alkenes with quinoxalin-2(1H)-ones and sodium sulfonates toward sulfone derivatives has been developed under environmentally friendly conditions. This strategy represents an efficient and practical difunctionalization of olefins using water/aqueous media as a sustainable solvent. In addition, this transition metal-free reaction is high yield, and operationally simple, and in particular, proceeds under mild conditions to afford desired sulfones with high functional group compatibility.

• 单位
  桂林理工大学