Maternal Cold-Reacting Immunoglobulin G Anti-M of MNS Blood Group System Causing Hemolytic Disease of the Fetus

作者:Liang, Yan-Lian; Shi, Yu; Su, Yu-Qing; Wu, Fan; Liang, Yanwen; Fan, Xiuchu; Lin, Jiansuo; Liu, Yi; Peng, Long; Ren, Jianwei; Liang, Shuang*
来源:Iranian Journal of Immunology, 2023, 20(1): 129-134.
DOI:10.22034/iji.2023.93993.2273.

摘要

Several cases of the hemolytic disease of the fetus and newborn (HDFN) caused by immunoglobulin G (IgG) anti-M antibodies have been reported, in which almost all the HDFN-associated anti-M were warmly reacting. Here we report two cases of severe HDFN associated with cold-reacting IgG anti-M. In both cases, pregnancy was terminated, in weeks 33 and 23 respectively, due to a diagnosis of fetal growth retardation (FGR). To our knowledge, these are the most severe HDFN cases caused by cold-reacting IgG anti-M.

  • 单位
    广东医学院; 中国科学院

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