A Novel Chromone Alcohol from Portulaca oleracea

作者：Zhang, Hongzhe; Wang, Chengyu; Han, Chunhui; He, Fan; Lan, Xiujuan; Leng, Aijing^*; Ying, Xixiang^*

来源：Chemistry of Natural Compounds, 2024, 60(1): 17-20.

DOI：10.1007/s10600-024-04242-5

• Portulaca oleracea L.
• chromone alcohol
• biological activity

A novel chromone alcohol, (S)-3,6,7-trihydroxy-2-(1-(4-hydroxyphenyl)ethyl)-4H-chromen-4-one, was isolated from Portulaca oleracea L. This compound was named oleracone P. The structure was identified by spectroscopic methods, including 1D, 2D NMR, CD, and UHPLC-ESI-Q-TOF/MS. It was found that oleracone P showed significant biological activity, inhibiting the production of inflammatory factor IL-1 beta at 20 mu M.

• 单位
  广东省人民医院; 广州中医药大学; 1