Rare-earth ions coordination enhanced ratiometric fluorescent sensing platform for quantitative visual analysis of antibiotic residues in real samples

作者：Xu, Shihao; Li, Lingfei; Lin, Dan; Yang, Liang^*; Wang, Zhenyang; Jiang, Changlong^*

来源：CHINESE CHEMICAL LETTERS, 2023, 34(6): 107997.

DOI：10.1016/j.cclet.2022.107997

• Rare-earth ions
• Ratiometric fluorescence probe
• Smartphone sensing platform
• Quantitative detection
• Levofloxacin

Levofloxacin (LVFX) as a representative drug of quinolone antibiotics is widely used in clinical, and its residues enriched in water bodies and sideline products seriously damage human health. It is impera-tive to develop a real-time/on-site sensing method for monitoring residual antibiotics. Here, we report a portable sensing platform by utilizing a composite fluorescent nanoprobe constructed by the cerium ions (Ce3 +) coordination functionalized CdTe quantum dots (QDs) for the visual and quantitative detection of LVFX residues. This fluorescent probe provides a distinct color variation from red to green, which shows a good linear relationship to LVFX residues concentrations in the range of 0-6.0 mu mol/L with a sensi-tive limit of detection (LOD) of 16.3 nmol/L. The smartphone platform with Color Analyzer App installed, which could accomplish quantified detection of LVFX in water, milk, and raw pork with a LOD of 27.9 nmol/L. The facile sensing method we proposed realizes rapid visualization of antibiotics residual in the environment and provides a practical application pathway in food safety and human health.

• 单位
  中国科学院