Long-Term Outcomes of Laparoscopic Surgery for Advanced Transverse Colon Cancer

作者：Zhao Liying; Wang Yanan; Liu Hao; Chen Hao; Deng Haijun; Yu Jiang; Xue Qi; Li Guoxin^*

来源：Journal of Gastrointestinal Surgery, 2014, 18(5): 1003-1009.

DOI：10.1007/s11605-014-2462-z

• Laparoscopic surgery
• Colon cancer
• Transverse colon
• Survival

The role of laparoscopic surgery for advanced transverse colon cancer (TCC) remains controversial, especially in terms of long-term oncologic outcomes.
This retrospective cohort study enrolled 157 consecutive patients who underwent curable resections for advanced TCC between January 2002 and June 2011 (laparoscopic-assisted colectomy (LAC), n = 74; open colectomy (OC), n = 83). Short-term outcomes and oncologic long-term outcomes were compared between the two groups.
Compared to the OC group, patients in the LAC group had less blood loss (LAC vs. OC, 79.6 +/- 70.3 vs. 158.4 +/- 89.3 ml, p < 0.001), faster return of bowel 2.6 +/- 0.7 vs. 3.8 +/- 0.8 days, p < 0.001), and shorter postoperative hospital stay (10.3 +/- 3.7 vs. 12.6 +/- 6.0 days, p = 0.007). Conversions were required in four (5.4 %) patients. Rates of short-term complication, mortality, and long-term complication were comparable between the two groups. The median follow-up time was 54 (26-106) months in the LAC group and 58 (29-113) months in the OC group (p = 0.407). There were no statistical differences in the rates of 5-year overall survival (73.6 vs. 71.1 %, p = 0.397) and 5-year disease-free survival (70.5 vs. 66.7 %, p = 0.501) between the two groups.
Laparoscopic surgery for advanced TCC yield short-term benefits while achieving equivalent long-term oncologic outcomes.

• 单位
  南方医科大学