Chinese guideline on the application of anti-seizure medications in the perioperative period of supratentorial craniocerebral surgery

作者：Liang, Shuli; Fan, Xing; Chen, Feng; Liu, Yonghong; Qiu, Binghui; Zhang, Kai; Qi, Songtao; Zhang, Guojun; Liu, Jinfang; Zhang, Jianguo; Wang, Jun; Wang, Xiu; Song, Ziyang; Luan, Guoming; Yang, Xuejun; Jiang, Rongcai; Zhang, Hua; Wang, Lei; You, Yongping; Shu, Kai; Lu, Xiaojie; Gao, Guoyi; Zhang, Bo; Zhou, Jian; Jin, Hai; Han, Kaiwei; Li, Yiming; Wei, Junji; Yang, Kun; You, Gan; Ji, Hongming; Jiang, Yuwu; Wang, Yi; Lin, Zhiguo; Li, Yan; Liu, Xuewu; Hu, Jie; Zhu, Junming; Li, Wenling

来源：Therapeutic Advances in Neurological Disorders, 2022, 15: 17562864221114357.

DOI：10.1177/17562864221114357

• anti-seizure medications (ASMs)
• craniocerebral surgery-related epilepsy
• craniocerebral surgery-related seizure
• guideline

Seizures are a common symptom of craniocerebral diseases, and epilepsy is one of the comorbidities of craniocerebral diseases. However, how to rationally use anti-seizure medications (ASMs) in the perioperative period of craniocerebral surgery to control or avoid seizures and reduce their associated harm is a problem. The China Association Against Epilepsy (CAAE) united with the Trauma Group of the Chinese Neurosurgery Society, Glioma Professional Committee of the Chinese Anti-Cancer Association, Neuro-Oncology Branch of the Chinese Neuroscience Society, and Neurotraumatic Group of Chinese Trauma Society, and selected experts for consultancy regarding outcomes from evidence-based medicine in domestic and foreign literature. These experts referred to the existing research evidence, drug characteristics, Chinese FDA-approved indications, and expert experience, and finished the current guideline on the application of ASMs during the perioperative period of craniocerebral surgery, aiming to guide relevant clinical practice. This guideline consists of six sections: application scope of guideline, concepts of craniocerebral surgery-related seizures and epilepsy, postoperative application of ASMs in patients without seizures before surgery, application of ASMs in patients with seizures associated with lesions before surgery, emergency treatment of postoperative seizures, and 16 recommendations.

• 单位
  四川大学; 中国医学科学院北京协和医院; 华中科技大学; 吉林大学; 清华大学; 复旦大学; 兰州大学; 浙江大学; 海南医学院; 北京大学; 苏州大学; 南方医科大学; 江南大学; 西安交通大学; 河北医科大学; 山东大学; 上海交通大学; 哈尔滨医科大学