Efficient hydrogenation of N-heteroarenes into N-heterocycles over MOF-derived CeO2 supported nickel nanoparticles

作者：Yuan, Ziliang; Li, Xun; Wang, Guanghui^*; Zhu, Zhihua; Liao, Yuhe^*; Zhang, Zehui; Liu, Bing^*

来源：Molecular Catalysis, 2023, 540: 113052.

DOI：10.1016/j.mcat.2023.113052

• Nickel nanoparticles
• Selective hydrogenation
• N-heterocycles
• Ceria oxide

The selective hydrogenation of N-heteroarenes into N-heterocycles is a highly important organic transformation in fine chemical industry, as N-heterocycles are moieties in a variety of pharmaceutical and bioactive com-pounds. Here, we report highly efficient mesoporous CeO2 supported Ni catalysts prepared by the incipient wet impregnation and following high-temperature reduction for the selective hydrogenation of N-heteroarenes. The experiments indicated that the synergistic effect between CeO2 and Ni nanoparticles was responsible to the superior catalytic performance. Various kinds of N-heterocycles were obtained at 120 degrees C with yields of 86 similar to >99%, demonstrating the versatility of the developed method. This work is valuable for guiding the design and manipulation of low metal loading, cost-effective and robust hydrogenation catalysts.

• 单位
  中国科学院; 中国科学院广州能源研究所