Relieving postoperative pain using tumescent solution with ropivacaine in follicular unit excision

作者：Dai, Da-mao; Qu, Qian; Fan, Zhe-xiang; Hu, Zhi-qi^*; Miao, Yong^*

来源：Journal of Cosmetic Dermatology, 2022, 21(10): 4697-4702.

DOI：10.1111/jocd.15011

• clinical research
• follicular unit excision
• postoperative pain
• ropivacaine
• tumescent anesthesia

Background Local tumescent anesthesia relieves postoperative pain. Objective The objective of the study was to compare the effect of injecting a tumescent solution with/without ropivacaine on postoperative pain. Methods A randomized, double-blind control study was conducted in 314 patients who underwent first follicular unit excision after obtaining informed consent and ethics committee approval. The patients were randomly divided into three groups: intra-groups (group 1, injected with tumescent solution with ropivacaine; group 2, without ropivacaine) and inter-group (group 3, right-head/left-head side with/without ropivacaine). Postoperative pain was recorded using the 5-point Wong-Baker Faces Pain Scale. No preoperative analgesic was administered to any patient. The survival rate of hair follicles was measured using dermoscopy during follow-up. Data were statistically analyzed. Results Of the 314 patients included in the study, 166 were men and 148 were women with a mean age of 32.15 +/- 4.58 (range, 25-45) years. Postoperative pain with ropivacaine was significantly more relieved compared with that without ropivacaine in both groups (p < 0.05). There was no significant difference between sex and survival rate of hair follicles in the intra- or inter-group. Conclusion A tumescent solution with ropivacaine has proven to relieve postoperative pain and is a safe and valuable form of local anesthesia in follicular unit excision.

• 单位
  南方医科大学; y