Biodegradable polymer network encapsulated polyplex for DNA delivery

摘要

A novel gene delivery system is made by encapsulation of a polyplex between pDNA and cationic micelles with a biodegradable crosslinked shell. The outer shell can provide additional functionality to the system and protect DNA from degradation. The encapsulated polyplex exhibits a similar transfection efficiency compared to the naked polyplex.

关键词