Carrier-free nanomedicines for cancer treatment

作者：Liu, Li-Han; Zhang, Xian-Zheng^*

来源：PROGRESS IN MATERIALS SCIENCE, 2022, 125: 100919.

DOI：10.1016/j.pmatsci.2021.100919

• Carrier-free
• Self assembly
• Nanomedicine
• Prodrug
• Tumor therapy

The last decade witnessed the great advances in the development of nanomedicines. As a kind of attractive nanomedicine, carrier-free nanomedicines received extensive investigations because of their high biosafety, high drug loading capacities, simple drug compositions and simplified synthetic procedures. Extensive efforts have been made to exploit more excipients and therapeutic agents, new self-assembly methods and therapeutic mechanisms to expand the scope of carrier-free nanomedicines with enhanced therapeutic performance. In this review, we summarized the research progress of carrier-free nanomedicines with practical applications in cancer therapy. Carrier-free nanomedicines were classified into three kinds, including free drugs,

• 单位
  Wuhan University; Southern Medical University