Photoinduced Pd-Catalyzed Dearomative 2,5-Difunctionalizition of Furans via Cascade C-C/C-O Bond Formation

作者：Long, Fen; Jiang, Kai; Song, Weiwei; Luo, Wenkun^*; Yin, Biaolin^*

来源：Organic Letters, 2024, 26(5): 1083-1087.

DOI：10.1021/acs.orglett.3c04345

• CHEMICALS
• REARRANGEMENT
• BIOMASS
• INDOLES
• RING

We report an efficient and mild approach for radical dearomatization via photoinduced palladium-catalyzed reaction of three components (i.e., furans, alcohols, and bromoalkanes). In this strategy, various functionalized spiro-heterocycles were prepared from furans in one step via cascade C-C/C-O bond formation under redox neutral conditions.

• 单位
  长沙理工大学