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H19: A Vital Long Noncoding RNA in the Treatment of Diabetes and Diabetic Complications

Zhu, Leiqi; Li, Yuanyang; Xia, Fangqi; Xue, Mengzhen; Wang, Yaqi; Jia, Dengke; Gao, Yan; Li, Luoying; Shi, Yue; Chen, Silong; Xu, Guangfu; Yuan, Chengfu*
Science Citation Index Expanded
中国医科大学

摘要

Background: Increasing academic efforts have been made to explore the correlation of long noncoding RNAs (lncRNAs) with human diseases, particularly metabolic diseases like diabetes mellitus. Taking lncRNA H19 as an example, this review intends to reveal the functions and mechanism of lncRNA H19 in diabetes mellitus and diabetic complications. Methods: The research results associated with lncRNA H19 and diabetes mellitus are collected and summarized on PubMed. Conclusion: LncRNA H19 is a potential instructive marker for the treatment of diabetes mellitus and diabetic complications.

关键词

H19 long noncoding RNA miRNA treatment hyperglycemia diabetes diabetic complications