H19: A Vital Long Noncoding RNA in the Treatment of Diabetes and Diabetic Complications

作者：Zhu, Leiqi; Li, Yuanyang; Xia, Fangqi; Xue, Mengzhen; Wang, Yaqi; Jia, Dengke; Gao, Yan; Li, Luoying; Shi, Yue; Chen, Silong; Xu, Guangfu; Yuan, Chengfu^*

来源：Current Pharmaceutical Design, 2022, 28(12): 1011-1018.

DOI：10.2174/1381612827666211210123959

• H19
• long noncoding RNA
• miRNA
• treatment
• hyperglycemia
• diabetes
• diabetic complications

Background: Increasing academic efforts have been made to explore the correlation of long noncoding RNAs (lncRNAs) with human diseases, particularly metabolic diseases like diabetes mellitus. Taking lncRNA H19 as an example, this review intends to reveal the functions and mechanism of lncRNA H19 in diabetes mellitus and diabetic complications. Methods: The research results associated with lncRNA H19 and diabetes mellitus are collected and summarized on PubMed. Conclusion: LncRNA H19 is a potential instructive marker for the treatment of diabetes mellitus and diabetic complications.

• 单位
  中国医科大学