The enormous repetitive Antarctic krill genome reveals environmental adaptations and population insights

作者：Shao, Changwei; Sun, Shuai; Liu, Kaiqiang; Wang, Jiahao; Li, Shuo; Liu, Qun; Deagle, Bruce E.; Seim, Inge; Biscontin, Alberto; Wang, Qian; Liu, Xin; Kawaguchi, So; Liu, Yalin; Jarman, Simon; Wang, Yue; Wang, Hong-Yan; Huang, Guodong; Hu, Jiang; Feng, Bo; Pitta, Cristiano De; Liu, Shanshan; Wang, Rui; Ma, Kailong; Ying, Yiping; Sales, Gabrielle; Sun, Tao; Wang, Xinliang; Zhang, Yaolei; Zhao, Yunxia; Pan, Shanshan; Hao, Xiancai; Wang, Yang; Xu, Jiakun; Yue, Bowen; Sun, Yanxu; Zhang, He

来源：Cell, 2023, 186(6): 1279-+.

DOI：10.1016/j.cell.2023.02.005

• GENETIC DIFFERENTIATION
• MOLECULAR EVOLUTION
• REFERENCE SEQUENCE
• PROTEIN FAMILIES
• READ ALIGNMENT
• DATABASE
• PROGRAM
• TOOL
• INFERENCE
• OCEAN

Antarctic krill (Euphausia superba) is Earth's most abundant wild animal, and its enormous biomass is vital to the Southern Ocean ecosystem. Here, we report a 48.01-Gb chromosome-level Antarctic krill genome, whose large genome size appears to have resulted from inter-genic transposable element expansions. Our assem-bly reveals the molecular architecture of the Antarctic krill circadian clock and uncovers expanded gene families associated with molting and energy metabolism, providing insights into adaptations to the cold and highly seasonal Antarctic environment. Population-level genome re-sequencing from four geographical sites around the Antarctic continent reveals no clear population structure but highlights natural selection associated with environmental variables. An apparent drastic reduction in krill population size 10 mya and a subsequent rebound 100 thousand years ago coincides with climate change events. Our findings uncover the genomic basis of Antarctic krill adaptations to the Southern Ocean and provide valuable resources for future Antarctic research.

• 单位
  i; 中国科学院研究生院; 深圳华大基因研究院; 测试单位