A new meroterpenoid and a new polyketide from Penicillium expansum GY618 Fungus

作者：Zhu, Qianheng; Zang, Yi; Luo, Juanjuan; Hou, Wen; Lei, Liang; Huang, Jiuzhong; Luo, Nianhua; Gao, Yanping; Ouyang, Sheng; Huang, Hao; Wen, Huiling^*

来源：Phytochemistry Letters, 2022, 51: 57-62.

DOI：10.1016/j.phytol.2022.07.004

• Penicillium expansum
• Meroterpenoid
• Polyketide

Two new compounds, including one meroterpenoid (1) and a polyketide derivative (2), along with six com-pounds (3-8), were isolated from the rice solid fermentation of Penicillium expansum GY618. The structures of these new compounds were elucidated through interpretations of spectroscopic data and highresolution elec-trospray ionization mass spectrometry. The absolute configurations of all new compounds were unambiguously established through the optical rotation or calculation of the ECD spectrum. All isolated compounds were evaluated for their antibacterial and antitumor activities. Compound 6 exhibited weak antitumor activity.

• 单位
  华中科技大学