Amphipathic poly-β-peptides for intracellular protein delivery

作者:Ren, Qianyi; Chen, Qi; Ren, Lanfang; Cao, Chuntao; Liu, Runhui*; Cheng, Yiyun*
来源:Chemical Communications, 2022, 58(27): 4320-4323.
DOI:10.1039/d2cc00453d

摘要

A series of amphipathic poly-beta-peptides are designed for intracellular protein delivery. The poly-beta-peptides with higher molecular weight and hydrophobic contents exhibit higher protein loading and superior delivery efficiency. The lead material efficiently delivers proteins into cells with reserved bioactivity.

  • 单位
    华东理工大学