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Amphipathic poly-β-peptides for intracellular protein delivery

Ren, Qianyi; Chen, Qi; Ren, Lanfang; Cao, Chuntao; Liu, Runhui*; Cheng, Yiyun*
Science Citation Index Expanded
华东理工大学

摘要

A series of amphipathic poly-beta-peptides are designed for intracellular protein delivery. The poly-beta-peptides with higher molecular weight and hydrophobic contents exhibit higher protein loading and superior delivery efficiency. The lead material efficiently delivers proteins into cells with reserved bioactivity.

关键词

DIRECT CYTOSOLIC DELIVERY