Intercepting a labile anti-π-allyl-iridium complex before its isomerization

Authors：Qu, Bao-Le; Zhang, Mao-Mao; Lu, Liang-Qiu^*; Xiao, Wen-Jing

Source：Chem, 2021, 7(3): 552-554.

DOI：10.1016/j.chempr.2021.02.022

• ALPHA-AMINO-ACIDS

The stereodefined installation of chiral centers adjacent to thermo-dynamically unstable Z-olefins is a challenge in synthetic chemistry. In a recent work published in Science, You and coworkers reported an iridium-catalyzed, Z-retentive asymmetric allylic allylation with a variety of Z-allyl esters, providing elegant access to important chiral Z-olefins.

• Institution
  中国科学院