科研之友
微信
新浪微博
Facebook
分享链接
摘要
A novel multicomponent cascade cyclization reaction inone potfor the preparation of pyrido[3,2-a]phenoxazin-5-onesfrom simple o-aminophenols, paraformaldehyde, andenaminones has been established. It is noteworthy that o-aminophenol plays multiple roles serving as both a bis-nucleophileand an iminoquinone precursor, which can in situ generate aminophenoxazinonesto undergo the Povarov reaction for the first time to yield pyrido[3,2-a]phenoxazin-5-ones with a high efficiency. Moreover, thephotoluminescence of pyrido[3,2-a]phenoxazin-5-oneshas polarity sensitivity and features aggregation-induced emission(AIE) characteristics, which is promising for bioimaging and theranosticapplications.
