Malignant myoepithelioma of the breast: a case report and review of literature

作者：Liang Yan Fang^*; Zeng Jin Cheng; Ruan Jian Bo; Kang Dong Ping; Wang Ling Mei; Chen Can; Xu Jun Fa; Wu Qiu Liang

来源：International Journal of Clinical and Experimental Pathology, 2014, 7(5): 2654-2657.

• Malignant myoepithelioma
• breast
• immunohistochemistry

In this article, we described a malignant myoepithelioma of the breast (MMB) in a 69-year-old woman. Breast cancer derived from myoepithelial cells is very rare, usually benign. The diagnosis of MMB based on histological and immunohistochemical finding. In this case, the author diagnosed the tumor as MMB, because tumor tissues were immunopositive for 34 beta E12, P63, SMA, S-100, CD10, E-Cad and Ki-67, and immunnegative for CK5/6, desmin, ER, PR and C-erbB-2, because tumor tissue showed invasive growth and local hemorrhage or necrosis, suggesting malignant, and also because there was a transition between the tumor cells and hyperplastic myoepithelium of non-tumorous ducts. The patient's postoperative recovery is smooth and regular following of patient is essential.

• 单位
  济南大学; 暨南大学; 东莞市人民医院