A fast-response turn-on quinoline-based fluorescent probe for selective and sensitive detection of zinc (II) and its application

作者：Wang, Jin-Tao; Pei, Ying-Ying^*; Yan, Ming-Yue; Li, Yu-Ge; Yang, Ge-Ge; Qu, Cong-Hui; Luo, Wen; Wang, Jia; Li, Qing-Feng^*

来源：Microchemical Journal, 2021, 160: 105776.

DOI：10.1016/j.microc.2020.105776

• Fluorescent probe
• Schiff base
• Quinoline
• Zn2+
• Test strips

A readily available Schiff base quinoline derivative, quinoline-2-carboxaldehyde (pyridine-2-carbonyl)-hydrazine (QCPCH), has been synthesized via a one-step condensation reaction. It is used as a turn-on fluorescent probe for detecting Zn2+ with high selectivity, sensitivity, and rapid response time of less than 3 s. In addition, the probe QCPCH shows a low detection limit of 72 nM and a large linear detection range (0-180 mu M). The mechanism of probe QCPCH for sensing Zn2+ is proposed to be based on the combined effects of chelation-induced enhanced fluorescence (CHEF) and inhibiting photoinduced electron transfer (PET); this is further demonstrated by the Job's plot analysis, Benesi-Hilde-brand study, FT-IR spectrum, and H-1 NMR titration. Furthermore, the QCPCH is successfully applied to determine Zn2+ in real water samples, and is made into test strips for fast, convenient, quantitative and qualitative detection of Zn2+.