Severe Cavitary Pneumonia Caused by Legionella pneumophila: a Case Report

Authors：Yang, Zhiwen; Yang, Wanhua^*

Source：Clinical Laboratory, 2023, 69(7): 1509-1512.

DOI：10.7754/Clin.Lab.2022.221114

• severe pneumonia
• Legionella
• cavity
• early molecular diagnosis
• long-term antibiotic therapy

Background: Pulmonary cavities caused by Legionella occur mainly in immunocompromised patients, and clinical information in patients with normal immune function is therefore limited. @@@ Methods: We report a 64-year-old female who developed a Legionella pulmonary cavity without any immunological abnormality. @@@ Results: She suffered severe pneumonia complicated by acute respiratory failure and acute renal insufficiency. Despite long-term antibiotic therapy, she showed signs of a life-threatening infection and a progressive pulmonary cavity. @@@ Conclusions: Our case report provided clinical data regarding the diagnosis and therapy of patients who develop Legionella pulmonary cavities without any underlying disease.