A metal-organic cage-based nanoagent for enhanced photodynamic antitumor therapy

摘要

Herein, we report, for the first time, a Pd6L8(NO3)(5.4)(ICG)(6.6) (ICG = indocyanine green) cage-based hexagonal nanoplate (3) via a combined nanoprecipitation and solid-state anion-exchange approach. Nanoplate 3 possesses enhanced near-infrared (NIR) light-triggered O-1(2) generation, high cellular uptake selective lysosome-targeting ability, and, consequently, excellent antineoplastic activity.

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