Blue Light Induced Insertion of Carbene into C(CO)-C Bonds of 1,3-Diones

摘要

Visible light is an ideal "tool" for the green chemical synthesis. Visible light-induced reactions show such advantages as mild reaction conditions, simple equipments and less by-products. Therefore, it has gradually become an important method in organic synthesis. Herein an blue light induced LiBr-promoted carbene insertion reaction of diazoesters into C(CO)-C bonds of 1,3-diones for the synthesis of a wide range of all-carbon quaternary center-containing 1,4-dione derivatives is reported. The method features good substrate universality and functional group compatibility, and therefore is an ideal and efficient strategy for the synthesis of 1,4-diones.

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