Uncovering the Mechanical Code of DNA Using 'Loop-seq'

作者：Marzec, Marek^*

来源：Trends in Genetics, 2021, 37(6): 494-495.

DOI：10.1016/j.tig.2021.02.004

• FRAGMENTS

DNA mechanical properties play a critical role in different biological processes. Basu and coworkers described a method that measures DNA mechanics on the genome scale. Access to a high-throughput tool for measuring DNA mechanics opens up new possibilities to investigate this phenomenon with respect to establishing the chromatin regulatory landscape.