科研之友
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摘要
Reported herein is an electrophile-modulated aromatization reaction of highly functionalized cyclopropanes to structurally diverse benzoisocoumarins featuring concurrent formation of the benzenoid and alpha-pyrone rings under mild conditions. An aromatization reaction of the proposed benzonorcaradiene intermediates prepared independently revealed a crucial role of the neighboring olefinic substituents in determining whether the cyclopropane ring expansion is followed by a 1,2-shift of the ester group.
