Molybdenum-silver co-catalyzed cycloaddition of alkynes with N-isocyanoiminotriphenylphosphorane (NIITP): an efficient strategy for the synthesis of monosubstituted pyrazoles

作者：Mi, Pengbing; Lang, Jiajia; Lin, Shaojian^*

来源：Chemical Communications, 2019, 55(55): 7986-7989.

DOI：10.1039/c9cc03363g

• 1,3-DIPOLAR CYCLOADDITION
• FUNCTIONAL ISOCYANIDES
• METAL-COMPLEXES
• DIAZOCARBONYL COMPOUNDS
• CASCADE REACTIONS
• DIAZO-COMPOUNDS
• ISOCYANOACETATES
• INHIBITOR
• CHEMISTRY
• INSERTION

A new molybdenum-silver co-catalyzed [3+2] cycloaddition of alkynes with N-isocyanoiminotriphenylphosphorane (NIITP) has been described. The NIITP serves as a non-toxic, facile "CNN" source. Over 30 substrates were successfully converted to the desired compounds in good to excellent yields.

• 单位
  电子科技大学; 四川大学; 南华大学