科研之友
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摘要
Multifunctional metabolites are widely involved in physiological and pathological processes as signaling molecules, sensors, epigenetic modification substrates and so on, in addition to being energy substances. In a recent Cell Research study, Wu et al. make a remarkable discovery that, when the level of 3-phosphoglycerate, a typical metabolite at the crossroads of glucose catabolism and serine anabolism, is low, the unoccupied 3-phosphoglycerate dehydrogenase is redirected to watch the cell fate.
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单位南方医科大学; 广东省人民医院
