Using uniformat and gene[rate] to analyze data with ambiguities in population genetics
Scopus
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摘要
Some genetic systems frequently present ambiguous data that cannot be straightforwardly analyzed with common methods of population genetics. Two possibilities arise to analyze such data: one is the arbitrary simplification of the data and the other is the development of methods adapted to such ambiguous data. In this article, we present an attempt at such a development, the uniformat grammar and the gene[rate] tools, highlighting the specific aspects and the adaptations required to analyze ambiguous nominal data in population genetics.
关键词
Ambiguous genetic data Data manipulation EM algorithm Frequency estimation Hardy-Weinberg Linkage disequilibrium
