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Metasurface-Based Abrupt Autofocusing Beam for Biomedical Applications

Luo, Yuan*; Tseng, Ming Lun; Vyas, Sunil; Kuo, Hsin Yu; Chu, Cheng Hung; Chen, Mu Ku; Lee, Hsiang-Chieh; Chen, Wen-Pin; Su, Vin-Cent; Shi, Xu; Misawa, Hiroaki; Tsai, Din Ping*; Yang, Pan-Chyr*
Science Citation Index Expanded
河北医科大学; 中国科学院; y

摘要

Manipulation and precise delivery of optical energies in the regions of interest within specimens require different strategies. Hence, proper control of input beam parameters is a prerequisite. One of the prominent methods is metasurface optics, capable of crafting properties of light at nanoscales. Here, the generation of an abrupt autofocusing (AAF) beam by a nanophotonic metasurface for biomedical applications is demonstrated. Fluorescence guided laser microprofiling of mouse cardiac samples is experimentally investigated, using the AAF beam to deliver optical energy selectively to specific locations. In addition, photocoagulation of ex vivo swine skin tissue is performed and observed through optical coherence tomography. The results show great potentials for integrating metasurface optics to realize miniature laser surgery instruments for wide applications in biomedicine.

关键词

abrupt autofocusing beam laser surgery metasurfaces