Base-promoted aerobic oxidative synthesis of fused 1,3,5-triazines under metal-free conditions

作者：Chen, Jinjin; Sun, Zhaozhao; Xiao, Fuhong; Deng, Guo-Jun^*

来源：Green Chemistry, 2020, 22(20): 6778-6782.

DOI：10.1039/d0gc02691c

• COVALENT TRIAZINE FRAMEWORKS
• ONE-POT SYNTHESIS
• MULTICOMPONENT REACTIONS
• BIOLOGICAL EVALUATION
• DERIVATIVES
• ALDEHYDES
• CYCLIZATION
• ANTICANCER
• INHIBITORS
• ANNULATION

An efficient base-promoted aerobic oxidation reaction for the synthesis of fused 1,3,5-triazines from 2-aminobenzimidazoles, aromatic aldehydes, and ammonium iodide has been developed. In this multi-component protocol, ammonium iodide served as a convenient nitrogen source and four C-N bonds were formed in one pot under metal-free conditions.

• 单位
  湘潭大学