Monodisperse BSA-conjugated zinc oxide nanoparticles based fluorescence sensors for Cu2+ ions

Authors：Chen Zhi^*; Wub Dudu

Source：Sensors and Actuators, B: Chemical , 2014, 192: 83-91.

DOI：10.1016/j.snb.2013.10.092

• Zinc oxide
• Bovine serum albumin
• Nanoparticles
• Probe
• Copper analysis

Bovine serum albumin conjugated zinc oxide nanoparticles (BSA-ZnO) were used as selective copper ions probes by fluorescence spectroscopic technique. The results showed that the fluorescence of the BSA-ZnO nanoparticles could be quenched only by Cu2+ in physiological buffer solution. The optimum fluorescence intensity was found to be at pH 7.0 with a temperature of 25 degrees C. Under these optimum conditions, the detection limit of Cu2+ ions was 6.09 x 10(-7) mol L-1. The effect of foreign ions on the fluorescence intensity of BSA-ZnO nanoparticles was also studied and foreign ions showed low interference response in detecting of Cu2+ ions. Moreover, the quenching was discussed to be a static quenching procedure, which was proved by quenching rate constant K-q (6.98 x 10(12) L mol(-1) s(-1)).

• Institution
  广东医学院