Isolation and characterization of sulfated polysaccharide from the Sargassum pallidum (Turn.) C. Ag. and its sedative/hypnotic activity

作者：Ji Aimin^*; Yao Yufa; Che Ou; Wang Bingjun; Sun Liang; Li Xiaodong; Xu Feng

来源：JOURNAL OF MEDICINAL PLANTS RESEARCH, 2011, 5(21): 5240-5246.

• Sargassum pallidum (Turn.) C. Ag
• polysaccharide
• sedative
• hypnotic

Sulfated polysaccharide from the Sargassum pallidum (Turn.) C. Ag. was isolated, purified and structurally characterized. The (13)C-NMR and IR indicated a characteristic sulfated polysaccharide with 16.4% of sulfate group. The isolated polysaccharide with the molecular range of 10 similar to 48 KDa was constituted by xylose (35.92%), mannose (21.86%), arabinose (15.26%), galactose (13.49%), glucose (9.60%) and others (3.88%). The animal experiment results suggested its potential sedative and hypnotic potential activity.

• 单位
  南方医科大学