A naphthimide-based ratiometric fluorescent probe for selective and visual detection of phosgene in solution and the gas phase

作者：Xu, Zhiqiang; Luo, Yabin; Hong, Yu; Liu, Ziru; Zhang, Ming-Xing^*; Gu, Shuang-Xi^*; Yin, Jun^*

来源：Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy , 2022, 269: 120789.

DOI：10.1016/j.saa.2021.120789

• Phosgene
• Fluorescent probe
• Ratiometric fluorescence signal
• Test strip

As a colorless, highly toxic and widely used chemical reagent, phosgene poses a potentially serious threat to public health and environmental safety. Therefore, there is an urgent need to develop a simple and sen-sitive method for detecting phosgene. In this work, a ratiometric fluorescent probe (NED) for phosgene was developed by utilizing 4-substituted 1,8-naphthimide unit as the fluorophore and ethylenediamine as the recognition moiety. The probe NED undergoes intramolecular cyclization reaction with phosgene, resulting in a remarkable ratiometric fluorescence response. The probe NED displays high sensitivity (LOD = 4.9 nM), excellent ratiometric fluorescence signal, and high selectivity toward phosgene over other relevant analytes. In addition, paper test strip capable of visually detecting gaseous phosgene has also been fabricated.

• 单位
  武汉工程大学