摘要

A mild and efficient method for the cobalt-catalyzed hydroxyperfluoroalkylation of alkenes has been developed. This method demonstrated broad substrate scope, good yields, and mild conditions with the tolerance of mono-, di-, and trisubstituted alkenes including both styrenes and non-activated aliphatic olefins. This strategy offered a valuable solution for rapid and efficient construction of beta-perfluoro-alkyl alcohols using widely available and inexpensive perfluoroalkyl bromides- and atmospheric oxygen.

  • 单位
    中山大学