Metal-Free Synthesis and Photophysical Properties of 1,2,4-Triarylpyrroles

作者：Chang, Dan; Chen, Jinjin; Liu, Yong; Huang, Huawen^*; Qin, Anjun^*; Deng, Guo-Jun^*

来源：Journal of Organic Chemistry, 2021, 86(1): 110-127.

DOI：10.1021/acs.joc.0c01788

• AGGREGATION-INDUCED EMISSION
• PYRROLE-DERIVED ALKALOIDS
• INDUCED ENHANCED-EMISSION
• SUBSTITUTED PYRROLES
• REAL-TIME
• CONSTRUCTION
• QUINOLINE
• COMPOUND
• AMINE

A three-component reaction has been developed for the construction of multiaryl-substituted pyrrole derivatives from arylketones, amines, and nitrovinylarenes under metal- free conditions. Hence, homologous 1,2,4-triaryl-substituted pyrrole products were obtained in good to high yields. Furthermore, 2,3,5-triaryl-substituted pyrroles were selectively formed in the absence of nitrovinylarenes. The photophysical properties of some pyrrole products have been investigated to show good aggregation-induced emission (AIE) activity.

• 单位
  湘潭大学