Aggregation-Induced Emission (AIE), Life and Health

作者：Wang, Haoran; Li, Qiyao; Alam, Parvej; Bai, Haotian; Bhalla, Vandana; Bryce, Martin R.; Cao, Mingyue; Chen, Chao; Chen, Sijie; Chen, Xirui; Chen, Yuncong; Chen, Zhijun; Dang, Dongfeng; Ding, Dan; Ding, Siyang; Duo, Yanhong; Gao, Meng; He, Wei; He, Xuewen; Hong, Xuechuan; Hong, Yuning; Hu, Jing-Jing; Hu, Rong; Huang, Xiaolin; James, Tony D.; Jiang, Xingyu; Konishi, Gen-ichi; Kwok, Ryan T. K.; Lam, Jacky W. Y.; Li, Chunbin; Li, Haidong; Li, Kai; Li, Nan; Li, Wei-Jian; Li, Ying; Liang, Xing-Jie

来源：ACS Nano, 2023, 17(15): 14347-14405.

DOI：10.1021/acsnano.3c03925

• aggregation-induced emission
• luminescent material
• bioimaging
• phototheranostics
• combined therapy
• detection
• monitoring
• biomedical application
• precision medicine

Light has profoundly impacted modern medicine and healthcare,withnumerous luminescent agents and imaging techniques currently beingused to assess health and treat diseases. As an emerging concept inluminescence, aggregation-induced emission (AIE) has shown great potentialin biological applications due to its advantages in terms of brightness,biocompatibility, photostability, and positive correlation with concentration.This review provides a comprehensive summary of AIE luminogens appliedin imaging of biological structure and dynamic physiological processes,disease diagnosis and treatment, and detection and monitoring of specificanalytes, followed by representative works. Discussions on criticalissues and perspectives on future directions are also included. Thisreview aims to stimulate the interest of researchers from differentfields, including chemistry, biology, materials science, medicine,etc., thus promoting the development of AIE in the fields of lifeand health.

• 单位
  北京理工大学; 山东大学; 南开大学; 东北林业大学; 南方医科大学; 中山大学; 华东理工大学; 南京大学; 1; 郑州大学; 中国科学院; 5; 吉林大学; 华中科技大学; y; i; 国家纳米科学中心; 浙江大学; 广州医学院; 武汉大学; 苏州大学; 西安交通大学; 南昌大学