Engineering a triplet exciton enhanced photoluminescence self-assembled nanoprobe containing block copolymer and Tb3+/Ga3+ complex for fluoride ion detection in serum

作者：Xie, Hangqing^*; Chen, Zi; Wei, Xiaoqin; Han, Qing; Wang, Haotuo; Yang, Xiaolei; Xu, Shiqing^*; Wang, Xiang^*

来源：Sensors and Actuators, B: Chemical , 2022, 366: 131975.

DOI：10.1016/j.snb.2022.131975

• Triplet exciton
• Self-assembled
• Tb-1@F127 nanoprobe
• Fluoride ion detection
• Serum

The fluoride ion (F-) concentration in serum is an important indicator of fluorosis. However, the biofluorescence of serum itself makes the concentration of F- difficult to detect. Herein, a Tb-1@F127 nanoprobe is synthesized by Flash NanoPrecipitation of Tb3+, Ga3+, organic ligands and block copolymer Pluronic (F127). The absorbance and photoluminescence (PL) of the Tb-1@F127 nanoprobe are enhanced by the "antenna " effect of the organic ligands and the energy transfer of triplet excitons. The molar extinction coefficient of Tb-1@F127 nanoprobe is 28,000 times higher than the f-f transfer in free Tb3+. Moreover, the addition of F- blocks the above energy transfer process, resulting in a decrease in the PL intensity of Tb-1@F127 nanoprobe. In the serum solution, the PL intensity of Tb-1@F127 nanoprobe has a linear response to the concentration of F- in the range of 0-18.81 ppm, and the detection limit is 0.056 ppm. The Tb-1@F127 nanoprobe demonstrates high sensitivity and selectivity for the detection of F- concentration, and is not affected by biological autofluorescence.