Transcription Profiles of Eimeria tenella Apical Membrane Antigen Gene, Etama

摘要

The invasion of Apicomplaxan parasite Eimeria tenella is a multistep process, after attaching the host cell, the tight junction complex is formed by proteins secreted from apical organelles, rhoptry (RONs) and microneme (Apical Membrane Antigen, AMA) between the parasite and host cell plasma membranes which is named as Moving Juction (MJ) and through which the parasite pulls itself into the host cell. In this study, researchers have used real-time quantitative RT-PCR to study the transcription profiles of Etama gene for the 1st time on eimeria parasites. The results showed that the transcription of Etama gene reached a peak during the sporozoites stage but it was very low during all other stages which is different from other Apicomplex parasites Etamal gene. So maybe there are other AMA family proteins in the Eimeria tenella which play a key role in the different stages, respectively.

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