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Aptamer-Based Cancer Cell Analysis and Treatment

Wu, Limei; Zhang, Yutong; Wang, Zhimin; Zhang, Yue; Zou, Jianmei*; Qiu, Liping*
Science Citation Index Expanded
桂林理工大学

摘要

Aptamers are a class of single-stranded DNA or RNA oligonucleotides that can exclusively bind to various targets with high affinity and selectivity. Regarded as "chemical antibodies", aptamers possess several intrinsic advantages, including easy synthesis, convenient modification, high programmability, and good biocompatibility. In recent decades, many studies have demonstrated the superiority of aptamers as molecular tools for various biological applications, particularly in the area of cancer theranostics. In this review, we focus on recent progress in developing aptamer-based strategies for the precise analysis and treatment of cancer cells.

关键词

aptamers cancer theranostics cell imaging cell recognition targeted therapy