Reduction-Specified Coupling Reactions of Nitroarenes by Heterogeneous Cobalt Catalysis

摘要

The in-depth study on reduction-specified coupling reactions of the nitroarenes by heterogeneous cobalt catalysis opens a door for diversified syntheses of functional N-containing molecules. Guided by the structure-function relationship of heterogeneous materials, rational design of nano-catalysts can effectively regulate the routes of organic reactions. Precise transformation of the intermediates generated during the nitroarene reduction with a suitable nano-catalyst is a promising way to develop new tandem reactions, and to synthesize structurally novel compounds that are of difficult access with the conventional approaches. @@@ Being different from conventional reductive coupling reactions of nitroarenes, structurally modifiable heterogeneous cobalt catalysts reveal excellent performance in precise use of a single intermediate during the catalytic transfer hydrogenation of the nitroarenes. This concept would provide a novel direction for the efficient utilization of nitroaromatics in the manufacture of high-value products. image

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