A soluble iron(ii)-phthalocyanine-catalyzed intramolecular C(sp3)-H amination with alkyl azides

作者：You, Tingjie; Zeng, Si-Hao; Fan, Jianqiang; Wu, Liangliang; Kang, Fangyuan; Liu, Yungen^*; Che, Chi-Ming^*

来源：Chemical Communications, 2021, 57(82): 10711-10714.

DOI：10.1039/d1cc04573c

• NITRENE TRANSFER-REACTIONS
• H BOND AMINATION
• NITROGEN-SOURCE
• ORGANIC AZIDES
• IRON
• REACTIVITY
• CHEMISTRY
• CATALYST

Herein, we describe a soluble iron(ii)-phthalocyanine, [Fe-II((Bu4Pc)-Bu-t)(py)(2)] (Pc = phthalocyaninato(2-)), as an effective catalyst in intramolecular C(sp(3))-H bond amination, with alkyl azides as the nitrogen source, to afford the amination products in moderate to excellent yields with a broad substrate scope.