Rapid Construction of Enantioenriched Benzofurochromanes by SaBOX/Copper(II) Catalyzed Enantioselective [3+2] Annulation of ?-Chromenes with Quinones

摘要

A rapid construction of enantioenriched benzofurochromanes was developed by SaBOX/copper(II) catalyzed enantioselective [3 + 2] annulation of gamma-chromenes with quinones. This process takes advantage of the simple starting materials and a highly efficient chiral SaBOX/copper(II) catalyst system, leading to a variety of benzofurochromanes in up to 96% yield with up to 97% ee.

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