科研之友
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摘要
Comprehensive Summary A rhodium-catalyzed denitrogenative carbonylation of 1,2,3-thiadiazole with alkynes to construct (benzo)thiochromenones is developed. Both terminal and internal alkynes were compatible in this [3+2+1] cycloaddition, affording a broad range of poly-substituted thiochromenones. Unsymmetrical alkyne substrates exhibited good regioselectivity. It is noteworthy that the present strategy could be used to construct both monocyclic and benzo-thiochromenones, and it is a novel example of denitrogenative transannulation with CO insertion.
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单位北京大学
