Loss of Thymine DNA Glycosylase Causes Dysregulation of Bile Acid Homeostasis and Hepatocellular Carcinoma

作者：Haider M. Hassan; Majdina Isovic; Bart Kolendowski; Natasha Bauer-Maison; Oladapo Onabote; Matthew Cecchini; Aaron Haig; Saman Maleki Vareki; T. Michael Underhill; Joseph Torchia

来源：Cell Reports, 2020, 31(1): 107475.

DOI：10.1016/j.celrep.2020.03.039

• thymine DNA glycosylase
• active DNA demethylation
• TET
• hepatocellular carcinoma
• FXR
• bile acids
• insulin resistance
• conditional deletion
• hepatoblastoma

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